The Space Between Reaction and Regulation
Collection Seven
Immunology and Inflammation
The two-way conversation between immunity and mood.
20
Articles
20
Published
0
Coming Soon
The Discipline
The two-way conversation between the immune system and the brain — cytokines, microglia, neuroinflammation, and the biology of sickness behavior.
Within Nervous System Intelligence
Mood is downstream of immunity as well as chemistry. NSI includes immunology so patients do not blame themselves for the biology beneath their symptoms.
Where to Start
A coherent first reading path.
One cross-disciplinary foundation and three anchor articles from this collection — read in this order for a full first pass.
Foundations of Nervous System Intelligence
2 cornerstone articles touch this discipline.
These are cross-disciplinary NSI Foundations. They also live in the master “NSI Foundations” library and are surfaced here because they carry this collection as a tag.
Article 13
The Biology of Uncertainty
Uncertainty is not merely an idea we hold in the mind — it is a physiological state, measurable in autonomic arousal, cortisol, and the biology of vigilance.
Article 59
What If Loneliness Is More Than an Emotion?
Loneliness is a chronic physiological state with distinct hormonal, immune, and neural signatures. It is a health condition, not a mood.
Reading Trail
A three‑article path through this collection.
For a reader who does not yet know where to begin. Three articles — read in order — open the discipline the way the founding editor would open it in a first conversation.
- 01
First Step
Neuroimmune Communication
Begin here — the doorway into this collection.
Read Article - 02
Middle Way
Exercise and Inflammation
The mid‑point — where the science begins to change how you look.
Read Article - 03
The Horizon
Immunology Within Nervous System Intelligence
The capstone — what the whole collection has been building toward.
Read Article
The articles
Showing 13–20 of 20 articles.
Loneliness and Immune Signaling
Loneliness and Immune Signaling within immunology and inflammation — the science, the human experience, and why it belongs inside Nervous System Intelligence as a practice.
Trauma Research and Inflammatory Markers
Trauma Research and Inflammatory Markers within immunology and inflammation — the science, the human experience, and why it belongs inside Nervous System Intelligence as a practice.
The Gut–Immune–Brain Relationship
The Gut–Immune–Brain Relationship within immunology and inflammation — the science, the human experience, and why it belongs inside Nervous System Intelligence as a practice.
Healing After Injury
Healing After Injury within immunology and inflammation — the science, the human experience, and why it belongs inside Nervous System Intelligence as a practice.
Hormones and Immunity
Hormones and Immunity within immunology and inflammation — the science, the human experience, and why it belongs inside Nervous System Intelligence as a practice.
Why Inflammation Is Not Inherently Bad
Why Inflammation Is Not Inherently Bad within immunology and inflammation — the science, the human experience, and why it belongs inside Nervous System Intelligence as a practice.
The Limits of Inflammation Claims
The Limits of Inflammation Claims within immunology and inflammation — the science, the human experience, and why it belongs inside Nervous System Intelligence as a practice.
Immunology Within Nervous System Intelligence
Immunology Within Nervous System Intelligence within immunology and inflammation — the science, the human experience, and why it belongs inside Nervous System Intelligence as a practice.
Research Evidence
10 peer-reviewed papers evidence this collection.
Drawn from the peer-reviewed Research Collection. Each entry opens on PubMed and carries a Nirva-relevance note written by the founding editor.
- Paper #82·2025·Research CollectionEffect of Mindfulness-Based Stress Reduction on Patients With Chronic Pain
Supports patient-focused mindfulness as a complementary element of chronic-pain care.
- Paper #85·2025·Research CollectionEffectiveness of Digital Lifestyle Interventions for Depression and Anxiety
Relevant to combining movement, sleep, self-monitoring, psychoeducation, and behavior-change support within a digital platform.
- Paper #87·2025·Research CollectionA Systematic Review of Logotherapy and Meaning-Centered Interventions for Women With Breast and Gynecological Cancer
Supports meaning reconstruction, quality of life, hope, and post-traumatic growth in women facing severe health adversity.
- Paper #90·2025·Research CollectionA Co-Produced International Qualitative Systematic Review of Trauma During Homelessness and Mental Health
Relevant to displacement, loss of safety, systemic trauma, dignity, and the need for survivor-informed services.
- Paper #81·2024·Research CollectionTelehealth Mindfulness-Based Interventions for Chronic Pain: A Randomized Clinical Trial
Scalable telehealth mindfulness programs improved pain-related functioning and biopsychosocial outcomes among veterans compared with usual care.
- Paper #83·2024·Research CollectionMindfulness Meditation for Fibromyalgia Syndrome: A Systematic Review and Meta-Analysis
Found low-to-moderate-certainty evidence for improvements in quality of life, stress, sleep, and depressive symptoms; conclusions should remain appropriately cautious.
- Paper #84·2024·Research CollectionThe Effect of Lifestyle Interventions on Anxiety, Depression and Stress: A Systematic Review and Meta-Analysis
Examined combined approaches involving physical activity, dietary change, sleep, and other health behaviors.
- Paper #86·2024·Research CollectionAdverse Childhood Experiences and Adult Mental-Health Outcomes: A Genetically Informed Cohort Study
Found that relationships between childhood adversity and adult mental health persisted after accounting for shared genetic and environmental factors.
Showing 8 of 10. All papers in these pillars are catalogued in the Research Library.