Nirva Institute · Astrocytes · Mental Health & Experience
Astrocytes and PTSD
An emerging biology alongside established circuit accounts.
PTSD is characterised by intrusive re-experiencing, hyperarousal, and altered threat learning. Established models focus on amygdala–prefrontal circuits; astrocyte contributions are increasingly under investigation.
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Astrocyte biology in fear learning
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What is not yet claimed
It cannot be inferred from current evidence that astrocyte pathology causes PTSD in humans. It can be inferred that astrocytes are part of the biological system in which trauma-related learning occurs.
Scientific References
Primary literature
AMA numeric style. Citation numbers are unified across the Nirva Life ecosystem — the same number refers to the same reference across every library article. Full registry is anchored in the Cornerstone Paper.
- 195.Adamsky A, Kol A, Kreisel T, et al. Astrocytic activation generates de novo neuronal potentiation and memory enhancement. Cell. 2018;174(1):59-71. PubMed ↗
- 209.Bang J, Kim HY, Lee H. Optogenetic and chemogenetic approaches for studying astrocytes and gliotransmitters. Exp Neurobiol. 2016;25(5):205-221. PubMed ↗
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