Nirva Institute · Astrocytes · Mental Health & Experience
Astrocytes and Stress Physiology
The cellular biology of a load the whole system carries.
Chronic stress produces measurable changes in brain structure and function. Astrocytes participate in these changes at multiple levels — from metabolic support to synaptic remodelling.
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Astrocytes and glucocorticoids
Astrocytes express glucocorticoid receptors and respond to stress hormones with functional and structural changes.182
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Implications for mental health
Scientific References
Primary literature
AMA numeric style. Citation numbers are unified across the Nirva Life ecosystem — the same number refers to the same reference across every library article. Full registry is anchored in the Cornerstone Paper.
- 182.Verkhratsky A, Nedergaard M. Physiology of astroglia. Physiol Rev. 2018;98(1):239-389. PubMed ↗
- 207.Rajkowska G, Stockmeier CA. Astrocyte pathology in major depressive disorder: insights from human postmortem brain tissue. Curr Drug Targets. 2013;14(11):1225-1236. PubMed ↗
- 209.Bang J, Kim HY, Lee H. Optogenetic and chemogenetic approaches for studying astrocytes and gliotransmitters. Exp Neurobiol. 2016;25(5):205-221. PubMed ↗
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